First International Conference on Medical Image Computing and Computer-Assisted Intervention
Massachusetts Institute of Technology, Cambridge MA, USA
October 11-13, 1998


General Information:
Tutorial registration will take place at Kresge Auditorium Lobby, on Saturday, beginning at 7:30AM. There will be continental breakfast food provided at registration.

Tutorials will take place in the Student Center. Lunch, which is provided for tutorial attendees, will be served at noon, on the 3rd floor of the Student Center, in the Mezzanine Lounge and 20 Chimneys Room. (there will be signs indicating lunch locations)

Four concurrent tutorials will be offered on Saturday, October 10, immediately preceding the conference.

Tutorial 1: Virtual Body Models and 3D Anatomy Atlases

Andreas Pommert, Thomas Schiemann, Louis Collins, Alex Zijdenbos

Starts at 1:00pm

"Virtual body models and 3D anatomy atlases"

Spatial body models based on tomographic images play an increasingly important role in medical research and education, planning of interventions, and simulation of procedures. This tutorial will present state-of-the-art methods for creating, representing, and exploring these models.

Specific topics that will be discussed include suitable data structures like "intelligent volumes" for integrating volume data and symbolic information. These structures are filled using volume segmentation and knowledge editing techniques. The resulting virtual body models are explored via volume visualization. Simulations can be performed using volume deformation methods or involving inference procedures within semantic networks. Variability of human neuro-anatomy and neuro-pathology is described with 3D probabilistic atlases. Methods for automatic generation of such models from MRI data will be presented.

Methods will be illustrated with various examples from body models based on radiological images as well as the anatomical Visible Human data. Typical applications include simulation of endoscopy and laparoscopy, planning of surgical procedures, authoring of multimedia documents, or interpretation support for PET studies and ultrasound images. The tutorial will include online demos of the scientific software VOXEL-MAN.

Intended audience: This tutorial is of specific interest to biomedical scientists (medical or technical) who are new to the field of virtual body models or are interested in expanding their knowledge in this field.

Tutorial 2: Object Shape

Stephen Pizer, Christopher Taylor, Timothy Cootes

Starts at 9:00am

Representations of the shape of anatomic objects appearing in medical images are useful in medical image object extraction (extract the liver-shaped object), registration of medical images (find the geometric transformation that makes the abdominal organs in an MR image fall upon those organs in a CT image), and studies of the relation of shape to disease (describe the shape sequence of the left ventricle that corresponds to hypokinesis of the apex of the endocardium). Shape is defined as those geometric and topological properties of an object that are equivariant to translation, rotation, and magnification. Typically shape has a significant statistical aspect, specifying the kind of variations in geometric properties that are likely within a particular shape and typically calculating probabilistic measures of the shape such as central tendency and measures of variability of the geometric properties using a set of training instances of the shape. In this tutorial we will set forth the position that shape lies in the statistical variations in the spatial properties of the relationships between neighboring object primitives. We will present models of shape based on a variety of primitives and mathematical and statistical approaches relevant to describing the spatial properties of these relationships. We will focus on four types of primitives on which there is much literature: landmarks; voxels; boundary points & normals; and medial points, widths, & boundary normals.

Reference will be made to the work not only of our own groups, but also Mardia & Dryden, Kendall, Bookstein, Grenander, Christensen, Zucker, Gerig, among others. The following outlines the presentation we plan. The presentation will be of mathematics, statistics, and algorithms, supported by illustrative results from medical image analysis and display. The major focus will be on objects in 3D images, such as organs, discrete brain structures, and patterns of structures such as brain gyri and blood vessels.

Tutorial 3: International Workshop on Soft Tissue Deformation and Tissue Palpation

Gabor Szekely and Jim Duncan

Starts at 8:30am

An understanding of elastic tissue deformation is becoming increasingly important in a wide range of medical applications such as surgical simulation and planning, telesurgery, or image guided surgery and diagnosis. The further development of these fields will critically depend on the availability of efficient methods and algorithms for the simulation of soft tissue deformation, the depth of understanding of the underlying physical processes, and the possibility to present the resulting surgical scene including geometrical, force, tactile and texture information to the user in a natural and pleasing manner.

These goals can only be achieved through coordinated research and development in a wide range of scientific and engineering disciplines including biomechanics, electrical and mechanical engineering, medical image acquisition, analysis and visualization, and computer science.

The goal of the workshop is to provide an information and discussion forum by overviewing the current state of the art in the aforementioned research areas and identifying the major trends and needs of the coming years. The meeting will be organized as a day-long accompanying tutorial of the MICCAI'98 conference. Invited lectures will cover the following major topics:
- Soft tissue biomechanics
- Approximation techniques for soft tissue deformation modeling
- Measurement of elastic tissue behavior
- Medical imaging techniques for elastometry
- Tissue property data bases
- Tissue deformation modeling in surgical simulators
- Modeling and simulation of tissue palpation
- Deformation models for dynamic systems

Programme Committee

N. Ayache, INRIA, Sophia Antipolis
B. Davies, Imperial College, London
S. Delp, Northwestern University
J. Duncan, Yale University, New Haven
S. Gibson, Mitshubishi Electric Research Lab, Boston
R. Howe, Harvard University, Cambridge
E. Keeve, Brigham and Women's Hospital, Boston
D. Metaxas, University of Pennsylvania
R. Robb, Mayo Clinic, Rochester
R. Satava, Yale University, New Haven
G. Szekely, ETH Zurich
R. Taylor, Johns Hopkins University
D. Terzopoulos, University of Toronto


8:30am- 9:50am Session on soft tissue biomechanics and tissue deformation modeling

8:30am- 9:10am A. McCulloch (UCSD): Soft tissue biomechanics

9:10am- 9:50am D. Terzopoulos (Univ. Toronto): Tissue deformation modelling

10:10am-11:30am Session on elastic tissue properties

10:10am-10:50am R. Ehman (Mayo Clinics): MR Elastometry

10:50am-11:30am F. Carter (Univ. Dundee): Biomechanical Testing of Intra-abdominal Soft Tissues

11:30am-12:30pm Round table discussion on tissue deformation modeling

1:30pm- 2:50pm Session on tissue palpation and surgical simulation

1:30pm- 2:10pm R. Howe (Harvard Univ.): Tissue palpation modeling

2:10pm- 2:50pm N. Ayache (INRIA, France): Tissue deformation modelling in surgical simulation

3:20pm- 4:30pm Session on the modelling of dynamic systems

3:20pm- 3:55pm J. Duncan (Yale Univ.): Heart modelling

3:55pm- 4:30pm D. Metaxas (Univ. Pennsylvania): Anatomical/physiological modelling of the cardiopulmonary system

4:30pm- 5:30pm Round table discussion on application aspects and future requirements/trends

Tutorial 4: Medical Image Analysis and Applications

organized by Eric Grimson and Ron Kikinis

Starts at 9:00am

This tutorial will feature presentations by selected international leaders in the field, summarizing the current state of the art in various aspects of medical image analysis, computer assisted interventions and other associated applications of the technology. Five major application areas will be covered: neurosurgery, orthopedics, neurological diseases, cardiology, and radiation therapy. For each session, one or two leaders in the area will describe key clinical and technical issues, current approaches, and areas of future opportunity. Speakers include David Hawkes (Guy's Hospital), Richard Bucholz (St. Louis), Tony DiGioia (Shadyside Hospital), Lutz Nolte (Bern), Guido Gerig (UNC), Martha Shenton (Harvard Med), Dimitris Metaxas (Penn), Leon Axel (Penn), Julian Rosenman (UNC) and Charles Pelizzari (Chicago).


9:00 -- 10:20 Computer assisted orthopedic surgery (Tony DiGioia and Lutz Nolte)

10:40 - 12:00 Computing in cardiac imaging (Dimitris Metaxas and Leon Axel)

1:00 -- 2:20 Radiation therapy(Julian Rosenman and Chuck Pelizzari)

2:20 -- 3:40 Image computing in neurologic diseases, especially schizophrenia (Martha Shenton and Guido Gerig)

4:00 -- 5:20 Image guided neurosurgery (Dave Hawkes and Richard Bucholz)